Neuroimmunology laboratory was founded in 1991.
Laboratory staff:
Evgeniya V. Markova, PhD, MD, the head of the laboratory
Ivan V. Savkin, researcher
Anna V. Smyk, junior researcher
Maria A. Knyazheva (Fomicheva), junior researcher
Olga S. Anikeeva, junior researcher
Natalia A. Korotkova, assistant – researcher
Scientific direction - the development of fundamental ideas about the mechanisms of immune and nervous systems functional integration in normal and pathological conditions; experimental study and developing radically new treatment strategies of the neuroimmunopathological processes.
The main priority results, obtained in the laboratory:
1) We have established the possibility and uncovered some mechanisms of action of cytokines, produced by immune cells, on the sensitive nerve endings; it revealed that immunegenesis is accompanied by increasing of the peripheral nerves axoplasmatic transport intensity, which opened up previously unknown the immune and nervous systems interaction channel (VV Abramov. The interaction of the immune and nervous systems. - Novosibirsk: Publishing house "Science" from 1988 to -164. (in Russian).
2) We demonstrated the ability of peripheral cytokines to accelerate the formation of conditioned reflexes in experimental animals, revealed the mechanisms underlying this ability, which was the starting point for the research processes of regulation of higher nervous activity on the part of the immune system (Abramov VV, Khichenko VI, Liuboslavskaia PN, Safronova OG . Effect of T-activin on the formation of conditioned reflex and manifestations of unconditioned reflex of avoidance in August strain rats. // Biull. Eksp. Biol. Med. 1992.- V.113(4).- P.397-399 (in Russian); VV Abramov. The integration of immune and nervous systems./ Novosibirsk, Nauka Publishers, Siberian, 1991. - 167 p. (in Russian).
3) We established the mechanisms and patterns of immunoregulatory properties of the parasympathetic autonomic nervous system, which greatly added the knowledge on the regulation of functional activity of the immune system by the central nervous system (VV Abramov. Interaction between the immune and nervous systems. Novosibirsk, Nauka Publishers, Siberian, 1988. - 164 p (in Russian); Sorokin, OV Markova EV, Abramov VV, Kozlov VA. The role of the autonomic nervous system in immune regulation in children // Neyroimmunologiya.- 2004.- V.2.- N. 1.- P. 45-48; Foundations of Neuroimmunology / Abramov VV et al - Moscow: Academy of Earth Sciences. Gold series of national scientific achievement, 2004.- 100 p (in Russian).
4) We showed the ability of the central nervous system regulation of antigen-specific immune response by the RNAs from the immunized animal’s brain. (VV Abramov, VA Kozlov Antigen-specific immunoregulatory effect of RNA from brain of immunised animals ./ Neuropeptides and Immunopeptides: Messengers in a Neuroimmune Axis. Annals of the New York Academy of Sciences, New York, 1990, p.367-368; VV Abramov, VA Mordvinov, VA Kozlov. Effect of RNA of the brain of immunized mice by specific immune response // Reports of USSR Academy of Sciences, 1990.-V.311.- N1.-P..243-245 (in Russian).
5) We identified and characterized the relationship between the parameters of higher nervous activity and quantitative and functional parameters of the immune system in healthy donors; we have established the clinical and immunological features of immunopathological processes in humans associated with the peculiarities of higher nervous activity and the activity of the autonomic nervous system divisions, which proves the ability to search for new approaches to the diagnosis and therapy of these diseases. (VV Abramov, T. Abramova, VS Kozhevnikov, et al. Interdependence between the parameters of human immunity and higher nervous activity/ //Dokl. Biol. Sci. - 2000. - V. 371. - N 1-6. - P. 115-117 (in Russian); Abramov VV, Abramova TY, Egorov DN, Vardosanidze KV. Higher nervous activity and immunity. Novosibirsk. - 2001 . – 123 p. (in Russian); OV Sorokin, EV Markova, VS Kozhevnikov, NM Starostin, VV Abramov, V.A. Kozlov. Prevention of immunodeficiency diseases in children of school age. Guidelines at the level of the RF Ministry of Health . Novosibirsk. – 2004 (in Russian).
6) We established proopiomelanokortin (POMK) gene expression in immune cells. (Foundations of Neuroimmunology / Abramov VV et al - Moscow: Academy of Earth Sciences. Gold series of national scientific achievement, 2004.- 100 p (in Russian).
7) We first demonstrated a new phenomenon of the directional changes in the parameters of exploratory behavior by the transplantation of immune cells with definite functional characteristics; we have established patterns of influence activation of cellular and humoral immune system on the behavioral parameters, that reveals the mechanisms of immune regulation behaviors (both congenital and acquired in the course of individual experience) and proves the ability to search for new approaches to therapy psihoneyroimmunopatological states. (Markova EV, Gromikhina N.Yu., Abramov VV, Kozlov VA. The peculiarities of the immune status in mice with different level of behavioral reactions // Russ. J. Immunology. - 2000. - V 5. - N 1. - P. 90-95; Markova EV, Korotkova NA, Abramov VV, Kozlov VA. Modulation of exploratory behavior in mice during activation of cell immune response. // Bull. Exp. Biol. Med. 2001.- V.132(4).- P.975-977;.EV Markova, VA. Kozlov, N.A Trofimova, N.G. Kolosova. Stimulation of Cell Component of the Immune Response Activates Exploratory Behavior in Senescence Accelerated OXYS Rats // Bull. Exp. Biol. Med.- 2005.- V.140.- N.3.-P.345-347; Abramov VV, Korotkova NA, Kozlov VA . Effect of transplantation of immunocompetent cell on oriental and exploratory behavior and cytokine gene expression in the brain of experimental animals. // Bull. Exp. Biol. Med.- 2006.- V.142.- N.3.- P.338 -340; Markova EV, Abramov VV, Ryabicheva TG, Kozlov VA. Effect of transplantation of splenic lymphoid cells on functional activity of the immune and nervous system in experimental animals.// Bull. Exp. Biol. Med. 2009 .- V. 147(4).-P.453-457; E. Markova, V. Abramov, V. Kozlov. Regulation of the behavior reactions by the immune cells transplantation. /Proceedings of the 2nd European Congress of Immunology. Free Papers. Editors Reinhold E. Schmidt.MEDIMOND Srl, Bolonga, Italy, 2009.- P. 551-555. Markov EV. The mechanisms of neuroimmune interactions in the behavioral reactions realization. Krasnoyarsk: Research and Innovation centre.- 2012.- 236 p. (in Russian).
8) We established the asymmetry of immune and neuroendocrine systems structural and functional unit. (Abramov VV, Gontova IA, Kozlov VA. Functional asymmetry of thymus and the immune response in mice // Neuroimmunomodulation. - 2001. - V 9. - N 4. - P. 218-224; Abramov VV, Gontova I. A. Abramov, T. Asymmetry of the hemispheres of the brain and lymphoid organs: role in hematopoiesis and immunegenesis // Functional hemispheric asymmetry. Moscow: Scientific World, 2004. - P. 523-543 (in in Russian); Abramov V.V., Gontova I.A., Kozlov V.A. Functional asymmetry in hematopoietic, immune and nervous systems / Behavioural and morphological asymmetries in vertebrates. Eds: Yegor Malashichev and A. Wallace Deckel. – 2006. - LANDES Bioscience. – Chapter 12. – p.148-159; Abramov VV, Gontova IA, Ignatiev IM, Gelfgat EL, Kozlov VA. Functional asymmetry of the cerebral hemispheres: its role in the pathogenesis of ectromelia and melanoma in (CBAxC57BL/6)F1 mice.// Neurosci. Behav. Physiol., 2010.- Sep;40(7).- P.733-736.
9) We have identified the opportunity and show correction mechanisms of immunological and behavioral disorders in chronic opioid dependence using transplantation of immune cells with certain functional characteristics (Markova EV, Abramov VV. Neuroimmunoregulation and new perspective in the correction of drug - induced behavior changes Building International Research: Emerging Trends and Pattern in drug Abuse Around the World Miami, Florida, 2003. - P. 45-47.34; Markova EV, Abramov VV, Starostina MV, Kozlov VA. Influence of immune cells transplantation on behavioral and immunological parameters in animals with chronic morphine dependence. // Drug Addiction, 2006.- № 5.- S.27-31 (in Russian); Markova EV, Starostina MV. Prospects of drug dependence immunotherapy / YM Ganeeva, TN Yusupova AN Garifzinoa etc. Actual problems of chemistry, biology and medicine. : monograph book 2. Krasnoyarsk:. Research and innovation centre.- 2011.- P.183-202(in Russian); Markova EV, Mihnevich NV, Starostina MV,Kozlov VA . Effect of immunomodulatory drugs on the formation of a chronic opiate dependence in laboratory animals // Siberian psychiatry and addiction bulletin, 2013.- № 5 (80), P.9 -. 13 (in Russian); Markova EV, Kozlov VA. The possibilities of cell therapy for opiate dependence // World of Science, Culture, Education, 2013.-№ 5 (42) .- P.410-412 (in Russian).
10) We first identified the opportunity and show correction mechanisms of depressive and aggressive-like behaviors in animals by the transplantation of immune cells, treated in vitro with psychoactive drugs (Markova EV, Knyazeva MA. Effect of the transplantation of splenocytes, treated with caffeine, on the behavior of experimental animals in the "open field" test // Herald of Ural Medical Academic nauki.- 2011.- № 2/1, (35) .- P. 36-37 (in Russian); Knyazheva MA, Ryzhikova SL, Ryabicheva TG, Markova EV. Effect of transplantation of immune cells treated with caffeine on the parameters of the functional activity of the nervous system // Bulletin of the East-Siberian Scientific Center of the SB RAMS, 2012.- V. 3 (85), part 2.-P. 284-287(in Russian); Markova EV, Knyazheva MA. Cytokine production by the brain cells of animals with a passive type of behavior after transplantation modulated caffeine immune cells // Russian Journal of immunologyl, V.9, 2015. (18) .- № 2 (1) .- P 88 – 90 (in Russian); Markova EV ., Knyazheva MA, Shushpanova TV Kozlov VA. Stimulation of the passive behavior of immune cells transplantation, treated in vitro with psychoactive drug .// Siberian bulletin Psychiatry and Addiction, 2015.-№4 (89) .- S.5-9 (in Russian).
The research results, obtained by the scientists of the laboratory, are regularly reported at the international congresses, published numerous articles, monographs in leading Russian and foreign editions.
Some publications (the period 2009 -2015):
Monographs:
1. VV Abramov, TY Abramova, AF Poveshchenko, VA Kozlov. Functional asymmetry of the immune, neuroendocrine and hematopoietic systems. Manual functional hemispheric asymmetry (group of authors), M .: World Scientific, 2009. - C. 274 – 302 (in Russian).
2. Archakov MK Batarchuk DS, Markova EV et al.. The social and humanitarian challenges of our time: people, society, and culture / Krasnoyarsk: Research and Innovation Centre.- 2011.- 202 p. (in Russian).
3. Markov EV The immune system and higher nervous activity. LAP LAMBERT Academic Publishing GmbH & Co. KG, Germany, 2012.- 260 c.
4. Ganeeva YM, Yusupova TN, AR Garifzyanov, Markova EV, et al.. Actual problems of chemistry, biology and medicine: a monograph. Book 2. / Krasnoyarsk: Research and Innovation Centre.- 2011.- 264 p. (in Russian).
5. Klimov TV, Markova EV Formation of a healthy way of life of the senior preschool children with disabilities / Krasnoyarsk: Research and Innovation Centre, 2012.- 240 p. (in Russian).
6. Markov EV Mechanisms nejroimmunnyh interactions in implementing behavioral / Krasnoyarsk: Research and Innovation Centre, 2012.- 236 p. (in Russian).
7. Evgeniya Markova, Vladimir Kozlov. Regulatory Role of Erythropoietin in Homeostatic Systems of the Body / Erythropoietin: Human Production, Potential Uses and Adverse Effects. Editors: Brian Macmillan and Walter Joiner. Nova Science Publishers, 2013.- Ch.1.- P. 31-54.
8. Smyk AV, Markova EV, fiefdom IS Psychophysiological aspects of asthma: approaches to psycho-correction. Novosibirsk: Publishing House of NSPU, 2013. – 86 p, (in Russian).
9. E. Markova, V. Kozlov, S. Roberts, C. Figuerello et al. Advances in genetics research / Editor Kevin V. Urbano, Nova Science Publishers, Inc, USA, 2013. -Vol. 10.- 198 p.
10. EV Markova. Behavior and Immunity. Novosibirsk: Publishing House of NSPU, 2013. - 165 p. (in Russian).
11. Anna Cmyk, Evgeniya Markova. Psychological and neyroimmunological aspects of the pathogenesis of asthma / Palmarium Academic Publishing, Omni Scriptum GmbH & Co. KG, Deutschland, 2015.- 134 p. (in Russian).
12. Chukhrova MG, Dresvyannikov VL, Markova EV. Drug addiction: modern strategy research. Saint-Louis, Missouri, USA: Publishing House Science and Innovation Center, 2015. - 218 p.
Collections of scientific works:
1. Markova EV, Abramov VV, Kozlov VA Regulation of exploratory behavior in (CBA x C57 / Bl / 6) F1 mice by the mononuclear phagocyte cells./ Cellular technology: Theoretical and applied aspects: Sat. scientific. tr. Ed. VA Kozlov, SV Sennikov, ER Chernich, AA Ostanin. Nauka, 2009.- 300 p. (in Russian).
2. Markova EV, Starostina MV, Abramov VV, Kozlov VA. Transplantation of immune cells as a possible method of correction of behavioral and immunological disorders in chronic morphine dependence. / Cellular technology: Theoretical and applied aspects: Sat. scientific. tr. Ed. VA Kozlov, SV Sennikov, ER Chernich, AA Ostanin. Nauka, 2009.- 300 p. (in Russian).
3. E. Markova, M. Starostina, V. Abramov, V. Kozlov. Immune Cell Transplantation: New Perspectives in the Correction of Morphine - Induced Immune and Behavior Disorders. / Proceedings of the 2nd European Congress of Immunology. Editors Reinhold E. Schmidt. MEDIMOND S.r.l., Bolonga, 2009, p. 423-429.
4. E. Markova, .V. Abramov, V. Kozlov. Regulation of the behavior reactions by the immune cells transplantation / Proceedings of the 2nd European Congress of Immunology. Editors Reinhold E. Schmidt. MEDIMOND S.r.l., Bolonga, Italy, 2009. - P. 551-555.
5. Knyazheva MA, Markova EV. Modulation of experimental animals behavior by the transplantation of immune cells treated with caffeine. / Contemporary Russian science through the eyes of young researchers: Proc. Nauchn. Editor JA Maksimov.- Krasnoyarsk: Publ: Research and Innovation Centre.- 2012.- pp 65-68. (in Russian).
6. Knyazheva MA, Markova EV Psycho modulating effect of the transplantation of immune cells, treated in vitro with neuroleptic / Education and Science of XXI Century. Medicine. Sofia. "Byal GRAD-BG" OOD, 2012-V. 36. -P.43-47. (in Russian).
7. E. Markova, M. Knyazeva, V. Kozlov. Immune parameters in mice with aggressive- and depressive-like behavior / Applied and Fundamental Studies: Proceedings of the 1st International Academic Conference Publishing House «Science and Innovation Center», International Journal of Advanced Studies. St. Louis, Missouri, USA, 2012. P. 21-27.
8. Markova E.V. New perspectives in the treatment of opiate dependence Competences of preschool teachers in knowledge society. The Third International Interdisciplinary Scientific Conference in Kikinda. Methodical Days 2014. Kikinda, October 25th, 2014. Proceedings book. Kikinda: High School Professional Studies in Education of Teachers, 2015 (Novo Milosevo: Garmond) 2015. - P. 102 - 107.
9. Markova E.V., Knyazheva M.A. Immune status peculiarities in experimental animals with aggressive- and depressive-like behavior // Psychological and pedagogical technologies in the context of innovative processes in medicine and education. Proceedings of the VI International Academic Conference, Turkey, Kemer, 2015. -P. 54 - 58.
Articles in scientific journals:
1. Markova EV, Abramov VV, Ryabicheva TG, Kozlov VA. Effect of Transplantation of Splenic Lymphoid Cells on Functional Activity of the Immune and Nervous System in Experimental Animals. // Bulletin of Experimental Biology and Medicine, 2009, V. 147.- N.4 .-Р.453-457
2. Markova EV, Abramov VV, Kozlov VA. Regulation of orienting-exploratory behavior in animals by transplantation of immunocompetent cells. // Successes of modern biology.- 2009.- V.129.- №.4- P.348-355. (in Russian).
3. Markova EV Fomicheva MA, Abramov VV, Kozlov VA. Parameters of the immune and nervous systems functional activities after the transplantation of immunet cells treated with neuroleptic drug. // Yakut Medical J.,2009.- № 3.- P.33-34(in Russian).
4. Markova EV, Abramov VV, Kozlov VA. Regulation of exploratory behavior in animals by the mononuclear phagocyte cells. // Herald of Ural Medical Academic Science.- 2009.- №2 / 1.-P.271-273 (in Russian).
5. Markova EV Starostina MV, Goldina IA, Abramov VV, Kozlov VA Correction of immunologic and behavioral disorders at a syndrome of chronic dependence on morphine by transplantation of immunet cells. // Herald of Ural Medical Academic Science.- 2009.- №2 / 1.-C. 217-219. (in Russian).
6. Goldin IA Gaydul KV Markova EV, Kozlov VA The cellular immune response and the effects of recombinant peptide homologous to the amino acid sequence of human endogenous retrovirus class I HERV E α 4-1. // Herald of Ural Medical Academic Science.- 2009.- №2 / 1.-C. 28-30. (in Russian).
7. Fomicheva MA, Markova EV, Abramov VV, Kozlov VA. Immunological and behavioral effects of the transplantation of splenocytes, treated with chlorpromazine in animals // Herald of Ural Medical Academic Science.- 2009.- №2 / 1.-S.56-58. (in Russian).
8. Solovieva IG, Korolenko TP., Gubina MA, Abramov VV. Psychoemotional features and gene polymorphism of dopamine-hydroxylase 444 G / A in patients with gastric cancer // Siberian psychiatry and narkology bulletin.- 2009.- 2 (53) .- S.78-80. (in Russian).
9. Markova EV, Abramov VV, Kozlov VA. Regulation of exploratory behavior in animals by transplanting immune cells .// The successes of modern biology, 2009.- V.129.- №.4- P.348-355 (in Russian).
10. Fomicheva MA, Ryabicheva TG. Cytokine production by the cells of the brain of experimental animals after transplantation of immune cells treated with neuroleptic agent // Herald of Ural Medical Academic Science. - 2010. - № 2/1. - S. 220-221. (in Russian).
11. E.V.Markova, V.V. Abramov, T.G.Ryabicheva, V.A. Kozlov. Effect of Transplantation of Splenic Lymphoid Cells on Functional Activity of the Immune and Nervous System in Experimental.// Bulletin of Experimental Biology and Medicine, 2009, V. -147.- N.4.-R.453-457.
12. Markova EV, Sorokin, OV, Kozlov VA. Features of the immune status and the possibility of rehabilitation therapy of children, suffering from chronic tonsillitis. // Yakut Medical J., 2010.- № 3.- P.19-21. (in Russian).
13. Abramov VV, Gontova IA, Ignatiev IM, Gelfgat EL, Kozlov VA. Functional asymmetry of the cerebral hemispheres: its role in the pathogenesis of ectromelia and melanoma in (CBAxC57BL / 6) F1 mice.// Neurosci. Behav. Physiol, 2010.- Sep;. 40 (7) .- P.733-736.
14. Markova EV Kolosova NG, Kozlov VA. Cellular immune response and orienting-exploratory behavior in experimental animals. // Herald of Ural Medical Academic Science. - 2010. - № 2/1. - S. 48-49. (in Russian).
15. Markova EV, Kozlov VA. Mechanisms of immunet cells regulation of (SBA x C57Bl / 6) F1 mice behavior // Herald of Ural Medical Academic Science. - 2010. - № 2/1. - S. 49-51. (in Russian).
16. Markova EV, Haldoyanidi SK, Orlovskaya IA. Immunological and behavioral characteristics of the offspring due to prenatal exposure to nicotine .// Russian Journal of immunological, 2011.- Volume 5 (14), № 3-4.- S.305-312. (in Russian).
17. M.A.Knyazheva, S.L.Ryzhikova, T.G.Ryabicheva, E.V.Markova. Effect of transplantation of immune cells treated with caffeine on the parameters of the nervous system functional activity // Bulletin of the East-Siberian Scientific Center of the SB RAMS, 2012.- N. 3 (85) .-Part 2.-P. 284-287. (in Russian).
18. Markova EV, Knyazheva MA, Kozlov VA. Cellular mechanisms of neuroimmune interactions in the regulation of exploratory behavior // Siberian Psychiatry and Addiction bulletin, 2013.-№ 1 (76) .- P. 49-52. (in Russian).
19. Smyk Markova EV. The original method of alexithymia correction based on body-oriented action // Modern Research of Social Problems, 2013.-№1 (13) .- P.169-173. (in Russian).
20. Smyk AV, Markova EV. Psychocorrectional effect in the treatment of bronchial asthma // In the world of scientific discoveries, 2013.-№7 (1) .- S.184-202. (in Russian).
21. Markova EV, Kozlov VA The possibilities of cell therapy for opiate dependence / World of Science, Culture, Education, 2013.-№ 5 (42) .- S.410-412.
22. Markova E.V., Knyazeva M.A., Kozlov V.A. Regulation of the behavior parameters in mice by the transplantation of immune cells with definite functional characteristics / International Journal of Advanced Studies. St. Louis, Missouri, USA, 2013. - P.9 - 13.
23. Smyk AV, Markova EV, Votchin IS. Features of patients with asthma respond to body-oriented psycho-correction, depending on the functional activity of the nervous system // In the world of scientific discoveries, 2013.-№ 11.4 (47) .- S. 362-370. (in Russian).
24. Markova E.V., Knyazheva M.A., Kozlov V.A. Modulation of oriented - exploratory behavioral parameters and cytokines synthesis in brain of mice-recipients after transplantation of caffeine treated immune cells // International Journal of Advanced Studies. USA, 2014. - P. 17 - 22.
25. Markova E.V., Smyk A.V., Knyazheva M.A., Rumina T.V. Lateral psychocorrection of anxiety in children, living in deprivation conditions // Modern Research of Social Problems, 2013.- N. 8 (28).
26. Markova E.V., Knyazheva M.A., Rumina T.V., Kozlov V.A. Immune cells functioning features in individuals with aggressive - and depressive - like behaviors // In the World of Scientific Discoveries, 2014.-V.2.-N2.-P. 45-55.
27. Anikeeva OS, Abramova T. Splenocytes functional characteristics in (CBAxC57 / Bl) F1 mice, formed under the influence of syngeneic immunet cells of adult animals with different levels of behavioral activity // Russian Journal of immunological, 2014.-T. 8 (17) .- №3.- P.256-258 (in Russian).
28. Markova EV Anikeeva O.S. Immune cells influence on the behavioral stereotypes formation in ontogenesis // In the world of scientific discoveries, 2015.-V. 2 (62) .- P. 154-170. (in Russian).
29. Anikeeva OS, Markova EV. The effects of repeated transplantation of the immune system on the parameters of behavior and intensity of immune responses in experimental animals // Inter-Medical. - 2015. - №2 (8). - C.4 - 7. (in Russian).
30. Markova EV, Smyk AV. Psychocorrectional effect in asthma and its influence on immunological parameters of patients // Russian Journal of immunological, 2015. -V.9, (18) .- N. 2 (1) .- P.316 - 317. (in Russian).
31. Markova EV, Knyazheva MA. Cytokine production by the brain cells of animals with passive type of behavior after the transplantation of immune cells modulated with caffeine // Russian Journal of immunological, 2015.- V.9 (18) .- № 2 (1) .- P. 88 - 90. (in Russian).
32. Smyk AV, Markova EV. Psychological adjustment in the treatment of bronchial asthma // Modern European Researches, 2015. - №5. - P. 108-110.
33. Idova GV, Markova EV, Gevorgyan MM, Alperina EL, Zhukova EM. Changes in spleen cells cytokines production in c57bl/6j mice with aggressive behavior induced by social stress. // Bulletin of Experimental Biology and Medicine, 2015T.160.- P.631-634 (in Russian).
34. Markova EV, Knyazheva MA, Shushpanova TV, Kozlov VA Stimulation of the passive behavior by the transplantation of immune cells, treated with psychoactive drugs // Siberian Psychiatry and Addiction bulletin, 2015.-№4 (89) .- P.5-9. (in Russian).
Cooperation: Neuroimmunology laboratory works closely with other laboratories of the Institute of Fundamental and Clinical Immunology, with the laboratories of other research institutes of the Siberian Branch of the Russian Academy of Sciences (Institute of Cytology and Genetics, Institute of Molecular Biology and Biophysics, Institute of Physiology and Fundamental Medicine, Mental Health research institute), NPO "Vector" .
International cooperation: Max Planck Institute (Germany), Institute of Integrative Medicine (Bordeaux, France).
Postal address: Neuroimmunology Lab.
State Research Institute of Fundamental and Clinical Immunology,
14 Yadrintzevskaya Str., Novosibirsk, 630099, Russia
Phone: +7 (383) 222 06 72
Fax: +7 (383) 222 70 28
e-mail: